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・ Epithele
・ Epithelial basement membrane dystrophy
・ Epithelial cell adhesion molecule
・ Epithelial cell rests of Malassez
・ Epithelial dysplasia
・ Epithelial polarity
・ Epithelial reticular cell
・ Epithelial root sheath
・ Epithelial Simple ciliated
・ Epithelial sodium channel
・ Epithelial sodium channel blocker
・ Epithelial-myoepithelial carcinoma
・ Epithelial-myoepithelial carcinoma of the lung
・ Epithelial–mesenchymal transition
・ Epithelioid
Epithelioid cell
・ Epithelioid cell histiocytoma
・ Epithelioid hemangioendothelioma
・ Epithelioid sarcoma
・ Epithelioma
・ Epithelioma cuniculatum
・ Epithelium
・ Epithelopsis
・ Epitherapis
・ Epitheria
・ Epitherina
・ Epithet
・ Epithets in Homer
・ Epithets of Jupiter
・ Epithisanotia


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Epithelioid cell : ウィキペディア英語版
Epithelioid cell

Epithelioid histiocytes (Epithelioid cells) are activated macrophages resembling epithelial cells: elongated, with finely granular, pale eosinophilic (pink) cytoplasm and central, ovoid nucleus (oval or elongate), which is less dense than that of a lymphocyte. They have indistinct shape contour, often appear to merge into one another and can form aggregates known as giant cells.
==Clinical significance==
Epithelioid cells are an essential characteristic of granulomas: that is to say that without them a histological finding is not a granuloma. A granuloma can be defined as "an organized collection of epithelioid macrophages." A non-purist would give a broader definition of the granuloma as "an organized collection of macrophages." The latter definition would include mere collections of giant cells surrounding inert substances like suture material – the so-called "non-immune granulomas."
Granuloma formation is a strategy that has evolved to deal with those pathogens that have learned to evade the host immune system by various means like resisting phagocytosis and killing within the macrophages. Granulomas try to wall off these organisms and prevent their further growth and spread. Many old scourges of mankind like tuberculosis, leprosy and syphilis fall into this category of diseases. Granuloma formation is also the feature of many of our newer problems like fungal infections, sarcoidosis and Crohn's disease.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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